> For the complete documentation index, see [llms.txt](https://netstim.gitbook.io/leaddbs/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://netstim.gitbook.io/leaddbs/lead-group/group-analyses-with-lead-dbs.md).

# Group analyses with Lead-DBS

{% hint style="info" %}
Lead group is best documented by [this paper](https://www.biorxiv.org/content/10.1101/2020.01.14.904615v1) and the accompanying walkthrough tutorial found on [OSF](https://osf.io/kj456/).

An older resource are [these walkthrough slides](https://www.lead-dbs.org/docs/tutorials/group_analyses_horn.pdf)
{% endhint %}

Once the coregistration, normalization and reconstruction steps have been performed for a group of patients, you can load these in the group GUI, which you can start by entering

`lead group`

into the MATLAB command line.

From here, several options for visualization and analysis of clinical/multimodal data are available. The rest of this section explains how to [Setup Analysis](/leaddbs/lead-group/setup-analysis.md), how to create [Group Visualization](/leaddbs/lead-group/group-visualization.md)s and how to [Calculate VTA and Stats](/leaddbs/lead-group/calculate-vta-and-stats.md).

{% hint style="info" %}
Before starting, please make sure to check accuracy of both normalization and reconstruction for each patient you analyse.
{% endhint %}

*Lead-Group GUI*

<figure><img src="/files/TNYtfaEgPxN81GqCpsMk" alt=""><figcaption></figcaption></figure>